Predicted winners and win likelihood for all possible matchups in the 2018 NCAA Men’s Basketball Tournament. Predictions generated on Monday, 3-12-2018.
| Team | Opponent | Seed | Opponent Seed | Predicted Winner | Likelihood of Win | |
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| 1 | Kansas | Villanova | 1 | 1 | Villanova | 0.764 |
| 2 | Kansas | Virginia | 1 | 1 | Virginia | 0.857 |
| 3 | Kansas | Xavier | 1 | 1 | Xavier | 0.596 |
| 4 | Kansas | North Carolina | 1 | 2 | North Carolina | 0.621 |
| 5 | Kansas | Purdue | 1 | 2 | Purdue | 0.653 |
| 6 | Kansas | Cincinnati | 1 | 2 | Cincinnati | 0.748 |
| 7 | Kansas | Duke | 1 | 2 | Duke | 0.774 |
| 8 | Kansas | Michigan | 1 | 3 | Michigan | 0.615 |
| 9 | Kansas | Michigan St. | 1 | 3 | Michigan St. | 0.652 |
| 10 | Kansas | Tennessee | 1 | 3 | Tennessee | 0.569 |
| 11 | Kansas | Texas Tech | 1 | 3 | Texas Tech | 0.578 |
| 12 | Kansas | Wichita St. | 1 | 4 | Kansas | 0.526 |
| 13 | Kansas | Arizona | 1 | 4 | Kansas | 0.561 |
| 14 | Kansas | Auburn | 1 | 4 | Auburn | 0.645 |
| 15 | Kansas | Gonzaga | 1 | 4 | Gonzaga | 0.652 |
| 16 | Kansas | Kentucky | 1 | 5 | Kansas | 0.54 |
| 17 | Kansas | Ohio St. | 1 | 5 | Ohio St. | 0.554 |
| 18 | Kansas | West Virginia | 1 | 5 | West Virginia | 0.513 |
| 19 | Kansas | Clemson | 1 | 5 | Clemson | 0.569 |
| 20 | Kansas | Miami FL | 1 | 6 | Kansas | 0.641 |
| 21 | Kansas | TCU | 1 | 6 | Kansas | 0.509 |
| 22 | Kansas | Florida | 1 | 6 | Florida | 0.501 |
| 23 | Kansas | Houston | 1 | 6 | Kansas | 0.533 |
| 24 | Kansas | Nevada | 1 | 7 | Kansas | 0.515 |
| 25 | Kansas | Rhode Island | 1 | 7 | Kansas | 0.67 |
| 26 | Kansas | Texas A&M | 1 | 7 | Kansas | 0.609 |
| 27 | Kansas | Arkansas | 1 | 7 | Kansas | 0.593 |
| 28 | Kansas | Missouri | 1 | 8 | Kansas | 0.653 |
| 29 | Kansas | Seton Hall | 1 | 8 | Kansas | 0.57 |
| 30 | Kansas | Virginia Tech | 1 | 8 | Kansas | 0.628 |
| 31 | Kansas | Creighton | 1 | 8 | Kansas | 0.558 |
| 32 | Kansas | Kansas St. | 1 | 9 | Kansas | 0.636 |
| 33 | Kansas | North Carolina St. | 1 | 9 | Kansas | 0.643 |
| 34 | Kansas | Alabama | 1 | 9 | Kansas | 0.665 |
| 35 | Kansas | Florida St. | 1 | 9 | Kansas | 0.621 |
| 36 | Kansas | Oklahoma | 1 | 10 | Kansas | 0.653 |
| 37 | Kansas | Providence | 1 | 10 | Kansas | 0.776 |
| 38 | Kansas | Texas | 1 | 10 | Kansas | 0.635 |
| 39 | Kansas | Butler | 1 | 10 | Kansas | 0.509 |
| 40 | Kansas | Loyola Chicago | 1 | 11 | Kansas | 0.651 |
| 41 | Kansas | San Diego St. | 1 | 11 | Kansas | 0.784 |
| 42 | Kansas | St. Bonaventure | 1 | 11 | Kansas | 0.74 |
| 43 | Kansas | Syracuse | 1 | 11 | Kansas | 0.698 |
| 44 | Kansas | UCLA | 1 | 11 | Kansas | 0.636 |
| 45 | Kansas | Arizona St. | 1 | 11 | Kansas | 0.671 |
| 46 | Kansas | Murray St. | 1 | 12 | Kansas | 0.748 |
| 47 | Kansas | New Mexico St. | 1 | 12 | Kansas | 0.738 |
| 48 | Kansas | South Dakota St. | 1 | 12 | Kansas | 0.793 |
| 49 | Kansas | Davidson | 1 | 12 | Kansas | 0.717 |
| 50 | Kansas | Marshall | 1 | 13 | Kansas | 0.899 |
| 51 | Kansas | UNC Greensboro | 1 | 13 | Kansas | 0.825 |
| 52 | Kansas | Buffalo | 1 | 13 | Kansas | 0.796 |
| 53 | Kansas | College of Charleston | 1 | 13 | Kansas | 0.875 |
| 54 | Kansas | Montana | 1 | 14 | Kansas | 0.81 |
| 55 | Kansas | Stephen F. Austin | 1 | 14 | Kansas | 0.93 |
| 56 | Kansas | Wright St. | 1 | 14 | Kansas | 0.928 |
| 57 | Kansas | Bucknell | 1 | 14 | Kansas | 0.871 |
| 58 | Kansas | Lipscomb | 1 | 15 | Kansas | 0.943 |
| 59 | Kansas | Cal St. Fullerton | 1 | 15 | Kansas | 0.943 |
| 60 | Kansas | Georgia St. | 1 | 15 | Kansas | 0.91 |
| 61 | Kansas | Iona | 1 | 15 | Kansas | 0.922 |
| 62 | Kansas | LIU Brooklyn | 1 | 16 | Kansas | 0.982 |
| 63 | Kansas | North Carolina Central | 1 | 16 | Kansas | 0.994 |
| 64 | Kansas | Penn | 1 | 16 | Kansas | 0.942 |
| 65 | Kansas | Radford | 1 | 16 | Kansas | 0.947 |
| 66 | Kansas | Texas Southern | 1 | 16 | Kansas | 0.986 |
| 67 | Kansas | UMBC | 1 | 16 | Kansas | 0.965 |
| 68 | Villanova | Virginia | 1 | 1 | Virginia | 0.638 |
| 69 | Villanova | Xavier | 1 | 1 | Villanova | 0.697 |
| 70 | Villanova | Kansas | 1 | 1 | Villanova | 0.764 |